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Program 1: Separation media and materials

The following projects are undertaken in the research area of
Program 1: Separation media and materials


Boronate affinity monoliths

Development of new polymeric monolithic stationary phases for affinity capillary electrochromatography based on boronic acid for the separation of glycoproteins. In collaboration with LBL Molecular Foundry, Berkeley.
Participants: Oscar Potter, Emily Hilder, Michael Breadmore


Monoliths for fast ion chromatography

Investigation of strategies for the preparation of high capacity latex-coated porous polymer monoliths as ion-exchange stationary phases with improved separation performance for fast ion chromatography and capillary ion chromatography. In collaboration with Dionex Corporation.
Participants: David Schaller, Emily Hilder, Pavel Nesterenko, Paul Haddad


In-line solid phase extraction capillary electrophoresis for direct determination of drugs in biological fluids

Synthesis of novel polymeric monolithic restricted-access materials for the selective adsorption of drugs and related metabolites from biological samples, suitable for in-line coupling with capillary electrophoresis and application to therapeutic drug monitoring.
Participants: Emily Hilder


Gold-selective ion exchange resins

Development of further ion-exchange resins with high selectivity towards gold (and silver) thiosulfate complexes, based on the use of magnetic ion exchange (MIEX®) resins.
Participants: Elijah Marshall, Greg Dicinoski, Paul Haddad


Preparation, characterisation and application of macro-, micro- and nanoporous inorganic monoliths

Participants: Michael Breadmore


Monoliths for trace enrichment

Development of new anionic chromatographic monolithic columns for the trace enrichment and separation of cationic target analytes, such as amino acids.
Participants: Emily Hilder, Michael Breadmore


New materials for HILIC

Application of novel grafted stationary phases hydrophilic interaction capillary electrochromatography. This is in collaboration with the University of Umeå.
Participants: Emily Hilder